Thalidomide-O-PEG2-propargyl

Thalidomide-O-PEG2-propargyl
Item number Size Datasheet Manual SDS Delivery time Quantity Price
TGM-T18826-2mg 2 mg

7 - 10 business days*

38.00€
 
Description: Thalidomide-O-PEG2-propargyl (E3 Ligase Ligand-Linker Conjugates 32) is a chemical... more
Product information "Thalidomide-O-PEG2-propargyl"
Description: Thalidomide-O-PEG2-propargyl (E3 Ligase Ligand-Linker Conjugates 32) is a chemical compound that has been synthesized as a conjugate of an E3 ligase ligand and a linker. It incorporates the cereblon ligand based on Thalidomide, along with a 2-unit PEG linker. This compound is specifically designed for use in PROTAC technology, which utilizes ligand-induced protein degradation [1]. Target: Others. Smiles: O=C1NC(=O)C(N2C(=O)C=3C=CC=C(OCCOCCOCC#C)C3C2=O)CC1. References: Wurz RP, et al. A "Click Chemistry Platform" for the Rapid Synthesis of Bispecific Molecules for Inducing Protein Degradation. J Med Chem. 2018 Jan 25,61(2):453-461.
Keywords: E3 ligase Ligand-Linker Conjugates 32
Supplier: TargetMol
Supplier-Nr: T18826

Properties

MW: 400.38 D
Formula: C20H20N2O7

Database Information

CAS : 2098487-52-4| Matching products

Handling & Safety

Storage: -20°C
Shipping: +20°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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