TH-263

Description: TH-263 is inactive toward both LIMK1 and LIMK2 and thus can be used as negative control for TH-257, and is a diaryl sulfonamide derivative. Target: Others. Smiles: S(NCC1=CC=CC=C1)(=O)(=O)C2=CC=C(C(NCC3=CC=CC=C3)=O)C=C2. References: Manetti F. Recent advances in the rational design and development of LIM kinase inhibitors are not enough to enter clinical trials. Eur J Med Chem. 2018 Jul 15,155:445-458.