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Description: TG-89 is an inhibitor of JAK2, JAK3, RET and FLT3, and has an IC50 value of 11.2 µM against JAK2, showing anticancer activity in the treatment of ovarian and cervical cancer. Target: JAK, FLT, c-RET. Smiles: Cc1cnc(Nc2cccc(CN3CCOCC3)c2)nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C. References: FURUKAWA Y, et al. Acute and subacute toxicities of azulene gargle (TG-89) containing azulene sodium sulfonate[J]. ORAL THERAPEUTICS AND PHARMACOLO GY, 1990, 9(3): 157-165.
This website uses cookies, which are necessary for the technical operation of the website and are always set. Other cookies, which increase the usability of this website, serve for direct advertising or simplify interaction with other websites and social networks, will only be used with your consent.
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