Cookie preferences
This website uses cookies, which are necessary for the technical operation of the website and are always set. Other cookies, which increase the comfort when using this website, are used for direct advertising or to facilitate interaction with other websites and social networks, are only set with your consent.
Configuration
Technically required
These cookies are necessary for the basic functions of the shop.
"Allow all cookies" cookie
"Decline all cookies" cookie
CSRF token
Cookie preferences
Currency change
Customer-specific caching
FACT-Finder tracking
Individual prices
Selected shop
Session
Comfort functions
These cookies are used to make the shopping experience even more appealing, for example for the recognition of the visitor.
Note
Show the facebook fanpage in the right blod sidebar
Statistics & Tracking
Affiliate program
Conversion and usertracking via Google Tag Manager
Track device being used

Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
Cay14963-1 | 1 mg | - |
6 - 10 business days* |
316.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
TTX is a potent marine-derived neurotoxin that reversibly inhibits the inward sodium current... more
Product information "Tetrodotoxin (citrate free)"
TTX is a potent marine-derived neurotoxin that reversibly inhibits the inward sodium current through voltage-activated sodium (NaV) channels, blocking nerve and muscle action potentials. It inhibits the NaV current in frog muscle and squid axon with IC50 values of 4.1 and 5.2 nM, respectively, and binds to rat brain membranes with a Kd value of 1.8 nM. TTX was used in Hodgkin and Huxley's classic experiments to elucidate the physical biology of nerve action potentials and remains an indispensible neuroscience tool to pharmacologically dissect the contribution of the NaV current in excitable neurons and to rationally design compounds for the treatment of neuropathic pain.Formal Name: (4R,4aR,5R,7S,9S,10S,10aR,11S,12S)-2-amino-1,4,4a,5,9,10-hexahydro-12-(hydroxymethyl)-5,9:7,10a-dimethano-10aH-[1,3]dioxocino[6,5-d]pyrimidine-4,7,10,11,12-pentol. CAS Number: 4368-28-9. Synonyms: Araregai Toxin, Maculotoxin, Tectin, TTX. Molecular Formula: C11H17N3O8. Formula Weight: 319.3. Purity: >98%. Formulation: (Request formulation change), A solid. Solubility: Acidic Buffer (pH 4.8): 3 mM. SMILES: NC1=N[C@H](O)[C@@]2([H])[C@]3([H])[C@](CO)(O)[C@]([H])([C@@]4([H])O)O[C@@](O)(O3)[C@@H](O)[C@@]24N1. InChi Code: InChI=1S/C11H17N3O8/c12-8-13-6(17)2-4-9(19,1-15)5-3(16)10(2,14-8)7(18)11(20,21-4)22-5/h2-7,15-20H,1H2,(H3,12,13,14)/t2-,3-,4-,5+,6-,7+,9+,10-,11+/m1/s1. InChi Key: CFMYXEVWODSLAX-QOZOJKKESA-N.
Keywords: | Araregai Toxin, Maculotoxin, Tectin, TTX, (4R,4aR,5R,7S,9S,10S,10aR,11S,12S)-2-amino-1,4,4a,5,9,10-hexahydro-12-(hydroxymethyl)-5,9:7,10a-dimethano-10aH-[1,3]dioxocino[6,5-d]pyrimidine-4,7,10,11,12-pentol |
Supplier: | Cayman Chemical |
Supplier-Nr: | 14963 |
Properties
Application: | NaV channel blocking |
MW: | 319.3 D |
Formula: | C11H17N3O8 |
Purity: | >98% |
Format: | Solid |
Database Information
CAS : | 4368-28-9| Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +20°C (International: -20°C) |
Signal Word: | Danger |
GHS Hazard Pictograms: |
![]() |
H Phrases: | H300, H310, H330 |
P Phrases: | P260, P262, P264, P270, P271, P280, P284, P320, P321, P330, P301+P310, P302+P352, P304+P340, P361+P364, P405, P403+P233, P501 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
more
You will get a certificate here
Viewed