Tenapanor
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You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Description: Tenapanor (RDX 5791) is an inhibitor of the sodium-proton (Na(+)/H(+)) exchanger... more
Product information "Tenapanor"
Description: Tenapanor (RDX 5791) is an inhibitor of the sodium-proton (Na(+)/H(+)) exchanger NHE3, which plays a prominent role in sodium handling in the gastrointestinal tract and kidney. Tenapanor possesses an excellent preclinical safety profile and, as of now, there are no serious concerns about its side effects. Target: Sodium Channel. Smiles: CN1C[C@@H](c2cccc(c2)S(=O)(=O)NCCOCCOCCNC(=O)NCCCCNC(=O)NCCOCCOCCNS(=O)(=O)c2cccc(c2)[C@@H]2CN(C)Cc3c(Cl)cc(Cl)cc23)c2cc(Cl)cc(Cl)c2C1. References: Johansson SA, Knutsson M, Leonsson-Zachrisson M, Rosenbaum DP. Effect of Food Intake on the Pharmacodynamics of Tenapanor: A Phase 1 Study. Clin Pharmacol Drug Dev. 2017 Mar 24. doi: 10.1002/cpdd.341. [Epub ahead of print] PubMed PMID: 28339149.
| Keywords: | AZD1722, AZD-1722, RDX5791, RDX 5791, RDX-5791, AZD 1722, Tenapanor free base |
| Supplier: | TargetMol |
| Supplier-Nr: | T7587 |
Properties
| Application: | Targets solute carrier family 9 (sodium/hydrogen exchanger), member 3 (SLC9A3, NHE3) |
| MW: | 1145.05 D |
| Formula: | C50H66Cl4N8O10S2 |
Database Information
| CAS : | 1234423-95-0| Matching products |
| KEGG ID : | K12040 | Matching products |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +4°C (International: +4°C) |
| Signal Word: | Warning |
| GHS Hazard Pictograms: |
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| H Phrases: | H371 |
| P Phrases: | P260, P264, P270, P308+311, P405, P501 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
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