tau-Fluvalinate

tau-Fluvalinate is a pyrethroid acaricide. It induces tail currents in Western honeybee (A. mellifera) voltage-gated sodium channels (AmNav1) expressed in Xenopus oocytes (EC50 = 60 nM). It also induces tail currents in honeybee parasitic Varroa mite (V. destructor) Nav1 channels (VdNav1) expressed in Xenopus oocytes (EC50 = 160 nM) with a faster tail current decay than that of AmNav1 channels. Topical application of tau-fluvalinate (2 µl) in combination with coumaphos (Cay-24230), atrazine (Cay-13375), 2,4-DMPF, chlorpyrifos (Cay-21412), and chlorothalonil (Cay-24142) does not affect honeybee queen mass, egg-laying patterns, or the mass of daughter worker bees at emergence. Formulations containing tau-fluvalinate have been used to control Varroa mites in beehives.Formal Name: N-[2-chloro-4-(trifluoromethyl)phenyl]-D-valine, cyano(3-phenoxyphenyl)methyl ester. CAS Number: 102851-06-9. Synonyms: tau-Fluvalinate. Molecular Formula: C26H22ClF3N2O3. Formula Weight: 502.9. Purity: >95%. Formulation: (Request formulation change), A liquid. Solubility: DMF: 10 mg/ml, DMSO: 10 mg/ml, Ethanol: 10 mg/ml. lambdamax: 256 nm. SMILES: FC(F)(F)C1=CC(Cl)=C(N[C@H](C(C)C)C(OC(C2=CC=CC(OC3=CC=CC=C3)=C2)C#N)=O)C=C1. InChi Code: InChI=1S/C26H22ClF3N2O3/c1-16(2)24(32-22-12-11-18(14-21(22)27)26(28,29)30)25(33)35-23(15-31)17-7-6-10-20(13-17)34-19-8-4-3-5-9-19/h3-14,16,23-24,32H,1-2H3/t23?,24-/m1/s1. InChi Key: INISTDXBRIBGOC-XMMISQBUSA-N.