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| Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
|---|---|---|---|---|---|---|---|
| Cay21155-500 | 500 µg | - |
6 - 10 business days* |
193.00€
|
|||
| Cay21155-1 | 1 mg | - |
6 - 10 business days* |
344.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
TASIN-1 is a small molecule inhibitor that specifically kills cells with adenomatous polyposis... more
Product information "TASIN-1"
TASIN-1 is a small molecule inhibitor that specifically kills cells with adenomatous polyposis coli (APC) truncations (IC50 = 70 nM) but spares cells with wild-type APC. TASIN-1 is effective in vivo, inhibiting tumor growth of colorectal cancer (CRC) cells with truncated APC, but not wild-type CRC cells, in a mouse xenograft model. TASIN-1 decreases cholesterol biosynthesis in APC-truncated cells but not in wild-type APC cells.Formal Name: 1'-[(4-methoxyphenyl)sulfonyl]-4-methyl-1,4'-bipiperidine. CAS Number: 792927-06-1. Molecular Formula: C18H28N2O3S. Formula Weight: 352.5. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 30 mg/ml, DMF:PBS (pH 7.2) (1:4): 0.2 mg/ml, DMSO: 15 mg/ml, Ethanol: 25 mg/ml. lambdamax: 241 nm. SMILES: CC1CCN(C2CCN(S(C3=CC=C(OC)C=C3)(=O)=O)CC2)CC1. InChi Code: InChI=1S/C18H28N2O3S/c1-15-7-11-19(12-8-15)16-9-13-20(14-10-16)24(21,22)18-5-3-17(23-2)4-6-18/h3-6,15-16H,7-14H2,1-2H3. InChi Key: XCBHYDPDIJQQGM-UHFFFAOYSA-N.
| Keywords: | 1'-[(4-methoxyphenyl)sulfonyl]-4-methyl-1,4'-bipiperidine |
| Supplier: | Cayman Chemical |
| Supplier-Nr: | 21155 |
Properties
| Application: | Colorectal cancer tumor growth inhibitor, APC-truncated cell toxin |
| MW: | 352.5 D |
| Formula: | C18H28N2O3S |
| Purity: | >98% |
| Format: | Crystalline Solid |
Database Information
| CAS : | 792927-06-1| Matching products |
| KEGG ID : | K02085 | Matching products |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +20°C (International: -20°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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