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Description: TA-01 is a potent inhibitor of CK1 and p38 MAPK, with IC50 values of 6.4 nM for CK1epsilon, 6.8 nM for CK1delta, and 6.7 nM for p38 MAPK. Target: Casein Kinase, p38 MAPK, Autophagy. Smiles: Fc1ccc(cc1)-c1nc([nH]c1-c1ccncc1)-c1c(F)cccc1F. References: Laco F, et al. Cardiomyocyte differentiation of pluripotent stem cells with SB203580 analogues correlates with Wnt pathway CK1 inhibition independent of p38 MAPK signaling. J Mol Cell Cardiol. 2015 Mar,80:56-70.
This website uses cookies, which are necessary for the technical operation of the website and are always set. Other cookies, which increase the usability of this website, serve for direct advertising or simplify interaction with other websites and social networks, will only be used with your consent.
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