T-2 Tetraol

T-2 tetraol is a trichothecene mycotoxin that has been found in F. tricinctum and an active metabolite of T-2 toxin (Cay-11444). It induces cell death (LC50 = 9 µg/ml), reduces proliferation (EC50 = 0.25 µg/ml), and decreases protein and DNA synthesis in primary human fibroblasts when used at a concentration of 10 µg/ml. T-2 tetraol is toxic to newly hatched chicks (LD50 = 33.79 mg/kg). It reduces feed consumption and weight gain in newly hatched chicks when administered at a dose of 40 mg/kg. T-2 tetraol has been found in Fusarium-contaminated barley kernels.Formal Name: 12,13-epoxy-trichothec-9-ene-3alpha,4beta,8alpha,15-tetrol. CAS Number: 34114-99-3. Synonyms: T-2 Toxin Tetraol. Molecular Formula: C15H22O6. Formula Weight: 298.3. Purity: >98%. Formulation: (Request formulation change), A powder. Solubility: Dichloromethane: 10 mg/ml. SMILES: CC1=C[C@]2([H])[C@]([C@]([C@H](O)[C@H]3O)(C)[C@@]4(OC4)[C@]3([H])O2)(CO)C[C@@H]1O. InChi Code: InChI=1S/C15H22O6/c1-7-3-9-14(5-16,4-8(7)17)13(2)11(19)10(18)12(21-9)15(13)6-20-15/h3,8-12,16-19H,4-6H2,1-2H3/t8-,9+,10+,11+,12+,13+,14+,15-/m0/s1. InChi Key: ZAXZBJSXSOISTF-LYFQSNBGSA-N.