Sulindac
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You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
An NSAID, a COX-2 inhibitor (IC50 = 0.79 µM), and a prodrug form of sulindac sulfide, selective... more
Product information "Sulindac"
An NSAID, a COX-2 inhibitor (IC50 = 0.79 µM), and a prodrug form of sulindac sulfide, selective for COX-2 over COX-1 (IC50 = >1,000 µM), inhibits acetic acid-induced writhing in mice and reduces carrageenan-induced paw edema in rats at 100 mg/kg, reduces tumor growth in a BxPC-3 mouse xenograft model at 60 mg/kg. Formulation: A crystalline solid. InChI: InChI=1S/C20H17FO3S/c1-12-17(9-13-3-6-15(7-4-13)25(2)24)16-8-5-14(21)10-19(16)18(12)11-20(22)23/h3-10H,11H2,1-2H3,(H,22,23)/b17-9-. InChIKey: MLKXDPUZXIRXEP-MFOYZWKCSA-N. SMILES: FC1=CC=C(/C(C(C)=C2CC(O)=O)=C\C3=CC=C(S(C)=O)C=C3)C2=C1
| Keywords: | 5-fluoro-2-methyl-1Z-[[4-(methylsulfinyl)phenyl]methylene]-1H-indene-3-acetic acid |
| Supplier: | Cayman Chemical |
| Supplier-Nr: | 10004386 |
Properties
| Application: | NSAID, COX-2 inhibitor |
| MW: | 356.4 D |
| Formula: | C20H17FO3S |
| Purity: | >98% |
| Format: | Crystalline Solid |
Database Information
| CAS : | 38194-50-2| Matching products |
| KEGG ID : | K11987 | Matching products |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +20°C (International: -20°C) |
| Signal Word: | Danger |
| GHS Hazard Pictograms: |
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| H Phrases: | H301, H317, H334, H361 |
| P Phrases: | P201, P202, P261, P264, P270, P272, P280, P284, P301+310, P302+352, P304+341, P308+313, P321, P330, P333+313, P342+311, P362+364, P405, P501 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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