STOML3 Inhibitor OB-1

STOML3 inhibitor OB-1 is an inhibitor of stomatin-like protein 3 (STOML3) oligomerization. It inhibits oligomerization of mouse and human STOML3 in cell-free assays when used at a concentration of 10 µM. STOML3 inhibitor OB-1 reduces Piezo1 channel current amplitude in Neuro2a cells. In vivo, STOML3 inhibitor OB-1 inhibits tactile perception in wild-type mice and reduces tactile allodynia in a mouse model of diabetic neuropathy induced by streptozotocin (Cay-13104).Formal Name: 5-[(1-methyl-4-nitro-1H-imidazol-5-yl)oxy]-2-phenyl-3-benzofurancarboxylic acid, ethyl ester. CAS Number: 300803-69-4. Synonyms: Stomatin-like Protein 3 Inhibitor OB-1. Molecular Formula: C21H17N3O6. Formula Weight: 407.4. Purity: >98%. Formulation: (Request formulation change), A solid. Solubility: DMSO: Soluble. lambdamax: 306 nm. SMILES: O=C(C1=C(C2=CC=CC=C2)OC3=C1C=C(OC4=C([N+]([O-])=O)N=CN4C)C=C3)OCC. InChi Code: InChI=1S/C21H17N3O6/c1-3-28-21(25)17-15-11-14(29-20-19(24(26)27)22-12-23(20)2)9-10-16(15)30-18(17)13-7-5-4-6-8-13/h4-12H,3H2,1-2H3. InChi Key: UJHGRDVYTTVJFD-UHFFFAOYSA-N.