SJ000063181
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Larger quantity required? Request bulk
SJ000063181 is a bone morphogenetic protein (BMP) signaling activator. It activates BMP4 in... more
Product information "SJ000063181"
SJ000063181 is a bone morphogenetic protein (BMP) signaling activator. It activates BMP4 in C33A-2D2 human cervical carcinoma clonal reporter cells (EC50 = =1 µM). SJ000063181 (6. µM) induces ventralization, as well as increases expression of the BMP target genes bmp2b and szl and the cooperatively induced BMP target genes vent and vox in zebrafish embryos. It also increases the stability of survival motor neuron protein (SMN, EC50 = 1. µM) in a reporter assay using the SMN2 gene, which produces an unstable truncated SMN protein.. Solulibility: DMSO: Sparingly Soluble: 1-10 mg/ml: Ethanol: Sparingly Soluble: 1-10 mg/ml.
| Keywords: | Ventromorphin 2, Vm2, N-(3-chloro-4-fluorophenyl)-5-(2-methylpropyl)-3-isoxazolecarboxamide |
| Supplier: | Cayman Chemical |
| Supplier-Nr: | 42546 |
Properties
| Application: | Bone morphogenetic protein (BMP) signaling activator |
| MW: | 296.72 D |
| Formula: | C14H14ClFN2O2 |
| Purity: | >98% |
| Format: | Solid |
Database Information
| CAS : | 945189-68-4| Matching products |
| KEGG ID : | K04662 | Matching products |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +20°C (International: -20°C) |
| Signal Word: | Warning |
| GHS Hazard Pictograms: |
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| H Phrases: | H315, H319, H335 |
| P Phrases: | P261, P264, P271, P280, P302+352, P304+340, P305+351+338, P312, P321, P332+313, P337+313, P362+364, P403+233, P405, P501 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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