Sekikaic Acid

Sekikaic acid is a phenolic lichen metabolite that has been found in H. obscurata and has diverse biological activities. It scavenges superoxide and DPPH (Cay-14805) radicals in cell-free assays when used at a concentration of 0.5 µM. Sekikaic acid is active against the rg recombinant strain of respiratory syncytial virus (RSV, IC50 = 5.69 µg/ml). It inhibits the protein-protein interaction between mixed lineage leukemia 1 (MLL1) and the GACKIX domain of CREB-binding protein (CBP, IC50 = 34 µM).Formal Name: 2-hydroxy-3-[(2-hydroxy-4-methoxy-6-propylbenzoyl)oxy]-4-methoxy-6-propyl-benzoic acid. CAS Number: 607-11-4. Molecular Formula: C22H26O8. Formula Weight: 418.4. Purity: >95%. Formulation: (Request formulation change), A solid. Solubility: DMSO: soluble, Ethanol: soluble, Methanol: soluble. SMILES: COC1=CC(CCC)=C(C(OC2=C(OC)C=C(CCC)C(C(O)=O)=C2O)=O)C(O)=C1. InChi Code: InChI=1S/C22H26O8/c1-5-7-12-9-14(28-3)11-15(23)17(12)22(27)30-20-16(29-4)10-13(8-6-2)18(19(20)24)21(25)26/h9-11,23-24H,5-8H2,1-4H3,(H,25,26). InChi Key: CPHXGYQLOSNELY-UHFFFAOYSA-N. Origin: Plant/Ramalina sp..