Sebetralstat

Item number	Size	Manual	Delivery time	Price
Cay45043-5	5 mg	-	6 - 10 business days*	88.00€
Cay45043-10	10 mg	-	6 - 10 business days*	133.00€
Cay45043-25	25 mg	-	6 - 10 business days*	242.00€
Cay45043-50	50 mg	-	6 - 10 business days*	395.00€

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A plasma kallikrein inhibitor (IC50 = 6 nM), selective for plasma kallikrein over a panel of 14... more

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Product information "Sebetralstat"

A plasma kallikrein inhibitor (IC50 = 6 nM), selective for plasma kallikrein over a panel of 14 additional proteases (IC50s = >10 µM for all), inhibits dextran sulfate-induced cleavage of kininogen-1 in isolated human plasma from 50-1,000 nM. SMILES: O=C1C=CC=CN1CC2=CC=C(CN3N=C(COC)C(C(NCC4=NC=CC(OC)=C4F)=O)=C3)C=C2. InChi Code: InChI=1S/C26H26FN5O4/c1-35-17-22-20(26(34)29-13-21-25(27)23(36-2)10-11-28-21)16-32(30-22)15-19-8-6-18(7-9-19)14-31-12-4-3-5-24(31)33/h3-12,16H,13-15,17H2,1-2H3,(H,29,34). InChi Key: KGMPDQIYDKKXRD-UHFFFAOYSA-N

Keywords:	KVD900, N-[(3-fluoro-4-methoxy-2-pyridinyl)methyl]-3-(methoxymethyl)-1-[[4-[(2-oxo-1(2H)-pyridinyl)methyl]phenyl]methyl]-1H-pyrazole-4-carboxamide
Supplier:	Cayman Chemical
Supplier-Nr:	45043

Properties

Application:	Plasma kallikrein inhibitor
MW:	491.52 D
Formula:	C26H26FN5O4
Purity:	>95%
Format:	Solid

Database Information

CAS :	1933514-13-6\| Matching products
KEGG ID :	K01324 \| Matching products

Handling & Safety

Storage:	-20°C
Shipping:	+20°C (International: -20°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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