(S)-CCG-1423

(S)-CCG-1423 is a stereoisomer of CCG-1423 (Cay-10010350), a Rho inhibitor that blocks signaling through myocardin-related transcription factor A (MRTF-A) and serum response factor (SRF). The S-isomer of CCG-1423 inhibits MRTF-A-dependent cellular events, including SRF-mediated gene expression and cell migration, more potently than the R-isomer.Formal Name: (S)-N-((1-((4-chlorophenyl)amino)-1-oxopropan-2-yl)oxy)-3,5-bis(trifluoromethyl)benzamide. CAS Number: 2319939-24-5. Molecular Formula: C18H13ClF6N2O3. Formula Weight: 454.8. Purity: >98%. Formulation: (Request formulation change), A solution in ethanol. Solubility: DMF: 10 mg/ml, DMSO: 10 mg/ml, DMSO:PBS (pH 7.2)(1:5): 0.15 mg/ml, Ethanol: 0.25 mg/ml. lambdamax: 249 nm. SMILES: O=C(NO[C@@H](C)C(NC1=CC=C(Cl)C=C1)=O)C2=CC(C(F)(F)F)=CC(C(F)(F)F)=C2. InChi Code: InChI=1S/C18H13ClF6N2O3/c1-9(15(28)26-14-4-2-13(19)3-5-14)30-27-16(29)10-6-11(17(20,21)22)8-12(7-10)18(23,24)25/h2-9H,1H3,(H,26,28)(H,27,29)/t9-/m0/s1. InChi Key: DSMXVSGJIDFLKP-VIFPVBQESA-N.