RS 67333 hydrochloride
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You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Description: RS 67333 hydrochloride (RO5203648) is a potent, selective partial agonist of the... more
Product information "RS 67333 hydrochloride"
Description: RS 67333 hydrochloride (RO5203648) is a potent, selective partial agonist of the 5-HT4 receptor (5-HT4R) with a pKi value of 8.7 in guinea-pig striatum. It demonstrates lower binding affinities for other receptors, including 5-HT1A, 5-HT1D, 5-HT2A, 5-HT2C, dopamine D1 and D2, and muscarinic M1-M3 receptors. Notably, RS 67333 hydrochloride exhibits neuroprotective properties, rendering it useful in Alzheimer's disease research. Target: 5-HT Receptor. Smiles: Cl.O=C(C=1C=C(Cl)C(N)=CC1OC)CCC2CCN(CCCC)CC2. References: R M Eglen, et al. Pharmacological characterization of two novel and potent 5-HT4 receptor agonists, RS 67333 and RS 67506, in vitro and in vivo. Br J Pharmacol. 1995 Aug,115(8):1387-92.
| Keywords: | RS 67333 (hydrochloride), RS 67333 HCl |
| Supplier: | TargetMol |
| Supplier-Nr: | T23265 |
Properties
| MW: | 389.36 D |
| Formula: | C19H30Cl2N2O2 |
Database Information
| CAS : | 168986-60-5| Matching products |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +20°C (International: +4°C) |
| Signal Word: | Warning |
| GHS Hazard Pictograms: |
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| H Phrases: | H302 |
| P Phrases: | P264, P270, P330, P301+P310, P501 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
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