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Description: RITA (NSC-652287)(NSC-652287) induced cross-links of both DNA-DNA and DNA-protein with no detectable DNA single-strand breaks. RITA, like nutlin-3, can disrupt the p53/Mdm2 interaction. Target: p53, Autophagy, Mdm2, DNA Alkylator/Crosslinker. Smiles: OCc1ccc(s1)-c1ccc(o1)-c1ccc(CO)s1. References: Rivera MI, et al. Biochem Pharmacol. 1999, 57(11), 1283-1295.
This website uses cookies, which are necessary for the technical operation of the website and are always set. Other cookies, which increase the usability of this website, serve for direct advertising or simplify interaction with other websites and social networks, will only be used with your consent.
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