Ribociclib succinate
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Description: Ribociclib succinate (LEE011 succinate) is a highly specific CDK4/6 inhibitor with... more
Product information "Ribociclib succinate"
Description: Ribociclib succinate (LEE011 succinate) is a highly specific CDK4/6 inhibitor with IC50 values of 10 nM and 39 nM, respectively, and exhibits over 1,000-fold reduced potency against the cyclin B/CDK1 complex. Target: CDK. Smiles: OC(=O)CCC(O)=O.CN(C)C(=O)c1cc2cnc(Nc3ccc(cn3)N3CCNCC3)nc2n1C1CCCC1. References: VanArsdale T, et al. Molecular Pathways: Targeting the Cyclin D-CDK4/6 Axis for Cancer Treatment. Clin Cancer Res. 2015 Jul 1,21(13):2905-10.
| Keywords: | LEE011 succinate |
| Supplier: | TargetMol |
| Supplier-Nr: | T15732 |
Properties
| Application: | Antineoplastic, Cyclin-dependent kinase (CDK) inhibitor |
| MW: | 552.63 D |
| Formula: | C27H36N8O5 |
Database Information
| CAS : | 1374639-75-4| Matching products |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +4°C (International: +4°C) |
| Signal Word: | Danger |
| GHS Hazard Pictograms: |
|
| H Phrases: | H301, H315, H319, H373 |
| P Phrases: | P260, P264, P270, P280, P314, P321, P330, P301+P310, P302+P352, P305+P351+P338, P332+P313, P337+P313, P362+P364, P405, P501 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
You will get a certificate here
Viewed