Repaglinide

Repaglinide
Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay19387-100 100 mg -

6 - 10 business days*

131.00€
Cay19387-250 250 mg -

6 - 10 business days*

311.00€
Cay19387-500 500 mg -

6 - 10 business days*

521.00€
Cay19387-1 1 g -

6 - 10 business days*

716.00€
 
Repaglinide is a metaglitinide antidiabetic agent that blocks ATP-dependent potassium (Kir6)... more
Product information "Repaglinide"
Repaglinide is a metaglitinide antidiabetic agent that blocks ATP-dependent potassium (Kir6) channels in pancreatic beta-cells (Kd = 0.42 nM for the sulphonylurea receptor SUR1 when co-expressed with Kir6.2). In vivo, repaglinide lowers blood glucose in fasted rats and dogs (ED50s = 10 and 28.3 µg/kg, respectively). Formulations containing repaglinide have been used to control blood sugar levels in patients with type 2 diabetes.Formal Name: 2-ethoxy-4-[2-[[(1S)-3-methyl-1-[2-(1-piperidinyl)phenyl]butyl]amino]-2-oxoethyl]-benzoic acid. CAS Number: 135062-02-1. Molecular Formula: C27H36N2O4. Formula Weight: 452.6. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 30 mg/ml, DMSO: 30 mg/ml, DMSO:PBS(pH 7.2) (1:4): 0.2 mg/ml, Ethanol: 25 mg/ml. lambdamax: 243, 293 nm. SMILES: CC(C[C@@H](C1=CC=CC=C1N2CCCCC2)NC(CC3=CC(OCC)=C(C=C3)C(O)=O)=O)C. InChi Code: InChI=1S/C27H36N2O4/c1-4-33-25-17-20(12-13-22(25)27(31)32)18-26(30)28-23(16-19(2)3)21-10-6-7-11-24(21)29-14-8-5-9-15-29/h6-7,10-13,17,19,23H,4-5,8-9,14-16,18H2,1-3H3,(H,28,30)(H,31,32)/t23-/m0/s1. InChi Key: FAEKWTJYAYMJKF-QHCPKHFHSA-N.
Keywords: 2-ethoxy-4-[2-[[(1S)-3-methyl-1-[2-(1-piperidinyl)phenyl]butyl]amino]-2-oxoethyl]-benzoic acid
Supplier: Cayman Chemical
Supplier-Nr: 19387

Properties

Application: Kir6 blocker
MW: 452.6 D
Formula: C27H36N2O4
Purity: >98%
Format: Crystalline Solid

Database Information

CAS : 135062-02-1| Matching products
KEGG ID : K05001 | Matching products

Handling & Safety

Storage: -20°C
Shipping: +20°C (International: -20°C)
Signal Word: Warning
GHS Hazard Pictograms:
H Phrases: H361, H362, H412
P Phrases: P201, P202, P260, P263, P264, P270, P273, P280, P308+313, P405, P501
Caution
Our products are for laboratory research use only: Not for administration to humans!
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