Regorafenib
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You can also order by e-mail: info@biomol.com
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You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Description: Regorafenib (BAY 73-4506) is an orally active, multi-targeted receptor tyrosine... more
Product information "Regorafenib"
Description: Regorafenib (BAY 73-4506) is an orally active, multi-targeted receptor tyrosine kinase inhibitor that inhibits RET, C-RAF, VEGFR2, c-Kit, VEGFR1, and PDGFRbeta, exhibiting both antitumor and anti-angiogenic activity. Target: PDGFR, Autophagy, Raf, c-RET, c-Kit, VEGFR. Smiles: CNC(=O)c1cc(Oc2ccc(NC(=O)Nc3ccc(Cl)c(c3)C(F)(F)F)c(F)c2)ccn1. References: Carr BI, et al. Fluoro-Sorafenib (Regorafenib) effects on hepatoma cells: growth inhibition, quiescence, and recovery. J Cell Physiol. 2013 Feb,228(2):292-7.
| Keywords: | Fluoro-Sorafenib, BAY 73-4506 |
| Supplier: | TargetMol |
| Supplier-Nr: | T1792 |
Properties
| Application: | Targets FMS-like tyrosine kinase 1 [EC:2.7.10.1] (FLT1, VEGFR1) |
| MW: | 482.82 D |
| Formula: | C21H15ClF4N4O3 |
Database Information
| CAS : | 755037-03-7| Matching products |
| KEGG ID : | K04362 | Matching products |
| Protein Atlas Nr. : | Tyrosine Phosphorylation |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +4°C (International: +4°C) |
| Signal Word: | Danger |
| GHS Hazard Pictograms: |
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| H Phrases: | H360, H362, H372, H400, H410 |
| P Phrases: | P201, P202, P260, P263, P264, P270, P273, P280, P314, P391, P308+P313, P405, P501 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
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