Radicicol

Radicicol
Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay13089-500 500 µg -

6 - 10 business days*

32.00€
Cay13089-1 1 mg -

6 - 10 business days*

50.00€
Cay13089-5 5 mg -

6 - 10 business days*

188.00€
 
Radicicol is an inhibitor of heat shock protein 90 (Hsp90, IC50 = erb82, and mutant p53.... more
Product information "Radicicol"
Radicicol is an inhibitor of heat shock protein 90 (Hsp90, IC50 = erb82, and mutant p53. Radicicol also binds to and inhibits DNA topoisomerase type II proteins and GRP94 through an ATPase domain common to Hsp90. Formal Name: (4E)-8-chloro-1aR,14R,15,15aR-tetrahydro-9,11-dihydroxy-14-methyl-6H-oxireno[e][2Z]benzoxacyclotetradecin-6,12(7H)-dione. CAS Number: 12772-57-5. Synonyms: KF9-A, KF58332, Monorden, NSC 294404. Molecular Formula: C18H17ClO6. Formula Weight: 364.7. Purity: >98%. Formulation: A crystalline solid. Solubility: DMSO: 20 mg/ml. lambdamax: 265 nm. SMILES: OC1=CC(O)=C(C(O[C@H](C)C[C@@H](O2)[C@H]2/C=C\C=C\C(C3)=O)=O)C3=C1Cl. InChi Code: InChI=1S/C18H17ClO6/c1-9-6-15-14(25-15)5-3-2-4-10(20)7-11-16(18(23)24-9)12(21)8-13(22)17(11)19/h2-5,8-9,14-15,21-22H,6-7H2,1H3/b4-2+,5-3-/t9-,14-,15-/m1/s1. InChi Key: WYZWZEOGROVVHK-GTMNPGAYSA-N.
Keywords: KF58332, KF9-A, Monorden, NSC 294404, (4E)-8-chloro-1aR,14R,15,15aR-tetrahydro-9,11-dihydroxy-14-methyl-6H-oxireno[e][2Z]benzoxacyclotetradecin-6,12(7H)-dione
Supplier: Cayman Chemical
Supplier-Nr: 13089

Properties

Application: Hsp90 inhibitor
MW: 364.7 D
Formula: C18H17ClO6
Purity: >98%
Format: Crystalline Solid

Database Information

CAS : 12772-57-5| Find alternatives
KEGG ID : K04079 | Find alternatives

Handling & Safety

Storage: -20°C
Shipping: +20°C (International: -20°C)
Signal Word: Danger
GHS Hazard Pictograms:
H Phrases: H301, H315, H319, H335
P Phrases: P261, P264, P270, P271, P280, P301+310, P302+352, P304+340, P305+351+338, P312, P321, P330, P332+313, P337+313, P362+364, P403+233, P405, P501
Caution
Our products are for laboratory research use only: Not for administration to humans!
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