R-1479

Description: R-1479 (4'-Azidocytidine) is an RdRp inhibitor with an IC50 value of 1.28 µM for HCV RNA replication in the HCV subgenomic replicon system. Target: HCV Protease. Smiles: Nc1ccn([C@@H]2O[C@@](CO)(N=[N+]=[N-])[C@@H](O)[C@H]2O)c(=O)n1. References: Klumpp K, et al. The novel nucleoside analog R1479 (4'-azidocytidine) is a potent inhibitor of NS5B-dependent RNA synthesis and hepatitis C virus replication in cell culture. J Biol Chem. 2006 Feb 17,281(7):3793-9.