Quin-2 (potassium salt)

Quin-2 is a high-affinity fluorescent calcium indicator (Kd = 115 nM for calcium). It displays high selectivity for calcium, as it is not affected by sodium gradients, membrane potential, or intracellular pH. High affinity probes like quin-2 are ideal for monitoring low levels of calcium, as are found in resting cells. Loadings of up to 2 mM quin-2 are without serious toxic effects, so quin-2 may be used to buffer intracellular calcium transients. Excitation/emission maxima for quin-2 are 339 and 492 nm, respectively.Formal Name: N-[2-[[8-[bis(carboxymethyl)amino]-6-methoxy-2-quinolinyl]methoxy]-4-methylphenyl]-N-(carboxymethyl)-glycine, tetrapotassium salt. CAS Number: 73630-23-6. Molecular Formula: C26H23N3O10 . 4K. Formula Weight: 693.9. Purity: >95%. Emission: 492 nm. Excitation: 339 nm. Formulation: (Request formulation change), A solid. Solubility: Water: soluble. SMILES: O=C([O-])CN(CC([O-])=O)C1=C2C(C=CC(COC3=C(N(CC([O-])=O)CC([O-])=O)C=CC(C)=C3)=N2)=CC(OC)=C1.[K+].[K+].[K+].[K+]. InChi Code: InChI=1S/C26H27N3O10.4K/c1-15-3-6-19(28(10-22(30)31)11-23(32)33)21(7-15)39-14-17-5-4-16-8-18(38-2)9-20(26(16)27-17)29(12-24(34)35)13-25(36)37,,,,/h3-9H,10-14H2,1-2H3,(H,30,31)(H,32,33)(H,34,35)(H,36,37),,,,/q,4*+1/p-4. InChi Key: XAGUNWDMROKIFJ-UHFFFAOYSA-J.