Pyropheophorbide a methyl ester

Pyropheophorbide a methyl ester is a photosensitizer and a derivative of chlorophyll a (Cay-33399). It induces cell death in RIF-1 cells when used in combination with photodynamic therapy (PDT) at concentrations of 0.06 and 1 µM. Pyropheophorbide a methyl ester localizes to cell membranes and induces IL-1 receptor internalization and NF-kappaB activation following light exposure in HCT116 cells.Formal Name: 9-ethenyl-14-ethyl-4S,8,13,18-tetramethyl-20-oxo-3S-phorbinepropanoic acid, methyl ester. CAS Number: 6453-67-4. Synonyms: Methyl pyropheophorbide a, NSC 267052, PPME. Molecular Formula: C34H36N4O3. Formula Weight: 548.7. Purity: >95%. Formulation: (Request formulation change), A solid. Solubility: Chloroform: slightly soluble, Methanol: slightly soluble when heated. lambdamax: 410, 667 nm. SMILES: O=C1CC(C2=C1C(C)=C(C=C3C(CC)=C(C)C(C=C4C(C=C)=C(C)C(N4)=C5)=N3)N2)=C6[C@@H](CCC(OC)=O)[C@H](C)C5=N6. InChi Code: InChI=1S/C34H36N4O3/c1-8-20-16(3)24-13-26-18(5)22(10-11-31(40)41-7)33(37-26)23-12-30(39)32-19(6)27(38-34(23)32)15-29-21(9-2)17(4)25(36-29)14-28(20)35-24/h8,13-15,18,22,35,38H,1,9-12H2,2-7H3/b24-13?,25-14-,26-13-,27-15-,28-14?,29-15?,33-23?/t18-,22-/m0/s1. InChi Key: RYLBYBPLWNFWPG-YLLYZGLVSA-N.