PTZ-343

PTZ-343 is a water-soluble enhancer of luminol (Cay-16803) chemiluminescent peroxidation catalyzed by horseradish peroxidase (HRP). It acts as an electron transfer mediator, reacting with HRP-II to release HRP and a PTZ-343 radical, which oxidizes luminol anions to induce light emission. HRP-induced chemiluminescent light emission increases by >800% in the presence of PTZ-343. It also enhances soybean peroxidase-induced chemiluminescence, increasing sensitivity and lowering the detection limit from 1.1 to 0.18 pM.Formal Name: 10H-phenothiazine-10-propanesulfonic acid, monosodium salt. CAS Number: 101199-38-6. Molecular Formula: C15H14NO3S2 . Na. Formula Weight: 343.4. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 20 mg/ml, DMSO: 20 mg/ml, PBS (pH 7.2): 10 mg/ml. lambdamax: 255, 312 nm. SMILES: [O-]S(CCCN1C2=C(C=CC=C2)SC3=CC=CC=C31)(=O)=O.[Na+]. InChi Code: InChI=1S/C15H15NO3S2.Na/c17-21(18,19)11-5-10-16-12-6-1-3-8-14(12)20-15-9-4-2-7-13(15)16,/h1-4,6-9H,5,10-11H2,(H,17,18,19),/q,+1/p-1. InChi Key: VKGYKXFNSKEHED-UHFFFAOYSA-M.