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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
CDX-P0234-M010 | 10 mg | - | - |
3 - 9 business days* |
77.00€
|
||
CDX-P0234-M100 | 100 mg | - | - |
3 - 9 business days* |
168.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Off-white to yellow powder. Soluble in DMSO (20 mg/ml), methanol (10 mg/ml), DMF (30 mg/ml) or... more
Product information "Pterostilbene"
Off-white to yellow powder. Soluble in DMSO (20 mg/ml), methanol (10 mg/ml), DMF (30 mg/ml) or ethanol (30 mg/ml). Insoluble in water. Chemical. CAS: 537-42-8. Formula: C16H16O3. MW: 256.3. Synthetic. Cell permeable natural methoxylated analog of resveratrol. Antioxidant, antiproliferative, anti-inflammatory, anti-hyperglycemic and anti-diabetic agent. Induces apoptosis. Induces Autophagy. Pterostilbene is a naturally-occurring dimethyl ether analog of resveratrol that is abundant in blueberries. Like resveratrol, pterostilbene acts as a powerful antioxidant, suppresses the synthesis of prostaglandin E2 from lipopolysaccharide-stimulated human peripheral blood mononuclear cells (IC50 = 1.0 µM for pterostilbene, 3.2 µM for resveratrol), and inhibits cell proliferation (IC50 = ~60 µM for both compounds). Very potent inhibitor of cytochrome P450 1A1 (CYP1A1) with Ki=0.57µM. Pterostilbene blocks the activation of ERK1/2, p38 MAPK, and PI3K/Akt signaling pathways, reducing NF-kappaB and AP-1 transcriptional activation. Moderately inhibits COX-1 and COX-2 (IC50=19.8µM and 83.9µM).
Keywords: | trans-3,5-Dimethoxy-4'-Hydroxystilbene, 4-[(1E)-2-(3,5-Dimethoxyphenyl)ethenyl]phenol, 3',5'-Dimethoxy-4-Stilbenol |
Supplier: | Chemodex |
Supplier-Nr: | P0234 |
Properties
MW: | 256,3 D |
Formula: | C16H16O3 |
Purity: | >97% (HPLC) |
Format: | Solid |
Database Information
CAS : | 537-42-8| Matching products |
Handling & Safety
Storage: | +4°C |
Shipping: | +20°C (International: +20°C) |
Signal Word: | Danger |
GHS Hazard Pictograms: |
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H Phrases: | H318, H411 |
P Phrases: | P273, P280, P305+P351+P338 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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