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| Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
|---|---|---|---|---|---|---|---|
| Cay22168-500 | 500 µg | - |
6 - 10 business days* |
223.00€
|
|||
| Cay22168-2.5 | 2500 µg | - |
6 - 10 business days* |
832.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Psoromic acid is an inhibitor of Rab geranylgeranyl transferase (IC50 = 1.3 µM) and P. falciparum... more
Product information "Psoromic Acid"
Psoromic acid is an inhibitor of Rab geranylgeranyl transferase (IC50 = 1.3 µM) and P. falciparum fatty acid synthesis (FAS) II. It shows cytotoxic effects on primary rat cerebral cortex and human cancer U87MG cell lines in vitro (IC50s = 79.40 and 56.22 mg/L, respectively). It also is cytotoxic against human KB cancer cells (IC50 = 31.6 µM). It shows moderate activity against liver stage P. beghei (IC50 = 31.6 µM) and drug-resistant blood stage P. falciparum (IC50 = 29.2 µM). The maximum tolerated dose in zebrafish larvae is 15.5 µM.Formal Name: 4-formyl-3-hydroxy-8-methoxy-1,9-dimethyl-11-oxo-11H-dibenzo[b,e][1,4]dioxepin-6-carboxylic acid. CAS Number: 7299-11-8. Synonyms: NSC 92186, Parellic Acid. Molecular Formula: C18H14O8. Formula Weight: 358.3. Purity: >95%. Formulation: (Request formulation change), A solid. Solubility: DMSO: Soluble, Ethanol: Soluble. SMILES: CC1=C(OC)C=C(C(O)=O)C(OC2=C3C(C)=CC(O)=C2C=O)=C1OC3=O. InChi Code: InChI=1S/C18H14O8/c1-7-4-11(20)10(6-19)15-13(7)18(23)26-14-8(2)12(24-3)5-9(17(21)22)16(14)25-15/h4-6,20H,1-3H3,(H,21,22). InChi Key: FUCWJKJZOHOLEO-UHFFFAOYSA-N. Origin: Fungus/Usnea sp..
| Keywords: | NSC 92186, Parellic Acid, 4-formyl-3-hydroxy-8-methoxy-1,9-dimethyl-11-oxo-11H-dibenzo[b,e][1,4]dioxepin-6-carboxylic acid |
| Supplier: | Cayman Chemical |
| Supplier-Nr: | 22168 |
Properties
| Application: | RABGGT inhibitor |
| MW: | 358.3 D |
| Formula: | C18H14O8 |
| Purity: | >95% |
| Format: | Solid |
Database Information
| CAS : | 7299-11-8| Matching products |
| KEGG ID : | K14050 | Matching products |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +20°C (International: -20°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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