PROTAC SMARCA2 degrader-4

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Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
TGM-T89436-10mg	10 mg	-	-	-	7 - 10 business days*		-
TGM-T89436-50mg	50 mg	-	-	-	7 - 10 business days*		-

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Description: PROTACSMAR CA2 degrader-4 (Compound I-424) is a PROTAC degradative agent targeting... more

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Product information "PROTAC SMARCA2 degrader-4"

Description: PROTACSMAR CA2 degrader-4 (Compound I-424) is a PROTAC degradative agent targeting the catalytic subunits SMARCA2 and SMARCA4 of the SWI/SNF complex. It effectively degrades SMARCA2 in MV411 and A549 cell lines with a DC50 of less than 100 nM and degrades SMARCA4 in MV411 with a DC50 exceeding 1 µM. Smiles: O=C(NCC=1C=CC(=CC1)C=2SC=NC2C)C3N(C(=O)C(NC(=O)C4CC5(C4)CC(N6CCC(C7=CN=C(N=C7)N8C9CN(C=%10C=C(N=NC%10N)C%11=CC=CC=C%11O)CC8CC9)CC6)C5)C(C)(C)C)CC(O)C3

Supplier:	TargetMol
Supplier-Nr:	T89436

Properties

MW:	1009.27 D
Formula:	C55H68N12O5S

Database Information

Handling & Safety

Storage:	+4°C
Shipping:	+4°C (International: +4°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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