Procyclidine hydrochloride

Procyclidine hydrochloride
Item number Size Datasheet Manual SDS Delivery time Quantity Price
CDX-P0608-G001 1 g - -

3 - 9 business days*

138.00€
CDX-P0608-G005 5 g - -

3 - 9 business days*

550.00€
 
Procyclidine is a synthetic anticholinergic agent and atropine-like antispasmodic. It exhibits... more
Product information "Procyclidine hydrochloride"
Procyclidine is a synthetic anticholinergic agent and atropine-like antispasmodic. It exhibits therapeutic effects against parkinson's disease and schizophrenia. Procyclidine is an antagonist of muscarinic acetylcholine receptors (Kis = 4.47, 42.66, 7.24, 6.03, and 4.79 nM for M1-5 receptors, respectively). It also affects N-methyl-D-aspartate (NMDA) glutamine and nicotinic acetylcholine receptors to a lower extent. Product References: (1) R.B. Barlow, et al., Br. J. Pharmacol. 72, 277 (1981) , (2) M. Waelbroeck, et al., Eur. J. Pharmacol. 189, 135 (1990) , (3) S. Lazareno, et al., Mol. Pharmacol. 38, 805 (1990) , (4) T. Zarnowski, et al., J. Neural. Transm. Gen. Sect. 97, 1 (1994) , (5) M.L. Sipos, et al., Psychopharmacol. 147, 250 (1999) , (6) V. Jevtovic-Todorovic, et al., Neuropharmacol. 44, 739 (2003) , (7) R. Roesler, et al., J. Clin. Psychopharmacol. 23, 666 (2003) Appearance: White to off-white powder. Solubility: Soluble in DMOS, DMF, ethanol (all 1mg/ml) or chloroform. Identity: Determined by 1H-NMR. InChi Key: ZFSPFXJSEHCTTR-UHFFFAOYSA-N Smiles: OC(C1CCCCC1)(CCN2CCCC2)C3=CC=CC=C3.Cl
Keywords: alpha-Cyclohexyl-alpha-phenyl-1-pyrrolidinepropanol, Arpicolin, Tricyclamol hydrochloride
Supplier: Chemodex
Supplier-Nr: P0608

Properties

Application: Antiparkinsonian, Muscarinic acetylcholine receptor antagonist
MW: 323.9 D
Formula: C19H29NO . HCl
Purity: >98% (TLC)
Format: Solid

Database Information

CAS : 1508-76-5| Matching products
KEGG ID : K04129 | Matching products

Handling & Safety

Storage: +4°C
Shipping: +20°C (International: +20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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