Primaquine (phosphate)

Primaquine is an established antimalarial drug used in the treatment of persistent liver forms of P. vivax or P. ovale infection for its ability to kill late-stage gametocytes and hypnozoites. In historical terms, this aminoquinoline was the stimulus for the discovery of glucose-6-phosphate (G6P) dehydrogenase deficiency as it induced hemolytic anemia in patients lacking the G6P-metabolizing enzyme.Formal Name: N4-(6-methoxy-8-quinolinyl)-1,4-pentanediamine, diphosphate. CAS Number: 63-45-6. Synonyms: NSC 149765. Molecular Formula: C15H21N3O . 2H3PO4. Formula Weight: 455.3. Purity: >95%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 0.5 mg/ml, DMSO: 10 mg/ml, PBS (pH 7.2): 10 mg/ml. lambdamax: 259, 349 nm. SMILES: COC1=CC(NC(C)CCCN)=C2C(C=CC=N2)=C1.O=P(O)(O)O.O=P(O)(O)O. InChi Code: InChI=1S/C15H21N3O.2H3O4P/c1-11(5-3-7-16)18-14-10-13(19-2)9-12-6-4-8-17-15(12)14,2*1-5(2,3)4/h4,6,8-11,18H,3,5,7,16H2,1-2H3,2*(H3,1,2,3,4). InChi Key: GJOHLWZHWQUKAU-UHFFFAOYSA-N.