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| Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
|---|---|---|---|---|---|---|---|
| Cay33390-1 | 1 mg | - |
6 - 10 business days* |
266.00€
|
|||
| Cay33390-5 | 5 mg | - |
6 - 10 business days* |
1,193.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
POMHEX is a prodrug form of the beta-enolase, also known as enolase-3, inhibitor HEX. It is... more
Product information "POMHEX"
POMHEX is a prodrug form of the beta-enolase, also known as enolase-3, inhibitor HEX. It is converted to HEX by intracellular carboxylesterases and selectively reduces the cell density of ENO1-/- D-423MG glioblastoma cells (IC50 = 38 nM) over ENO1-overexpressing D-423MG cells and LN-319 astrocytoma cells expressing wild-type ENO1 (IC50s = 604 and 2,148 nM, respectively). POMHEX decreases cell density in normoxic and hypoxic growth conditions in ENO1-/- D-423MG cells (IC50s = 79 and 201 nM, respectively).Formal Name: 2,2-dimethyl-propanoic acid, 1,1'-[[(1-hydroxy-2-oxo-3-piperidinyl)phosphinylidene]bis(oxymethylene)] ester. CAS Number: 2004714-34-3. Molecular Formula: C17H30NO9P. Formula Weight: 423.4. Purity: >98%. Formulation: (Request formulation change), A solid. Solubility: DMSO: Soluble. SMILES: O=C(C(C)(C)C)OCOP(OCOC(C(C)(C)C)=O)(C1C(N(CCC1)O)=O)=O. InChi Code: InChI=1S/C17H30NO9P/c1-16(2,3)14(20)24-10-26-28(23,12-8-7-9-18(22)13(12)19)27-11-25-15(21)17(4,5)6/h12,22H,7-11H2,1-6H3. InChi Key: TVFIFFUSHZDTKT-UHFFFAOYSA-N.
| Supplier: | Cayman Chemical |
| Supplier-Nr: | 33390 |
Properties
| Application: | Enolase-3 inhibitor HEX prodrug form |
| MW: | 423.4 D |
| Formula: | C17H30NO9P |
| Purity: | >98% |
| Format: | Solid |
Database Information
| CAS : | 2004714-34-3| Matching products |
| KEGG ID : | K01689 | Matching products |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +20°C (International: -20°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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