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Description: Pim-1/2 Kinase Inhibitor 1, an orally active inhibitor, impedes the action of Pim kinases by preventing their ability to phosphorylate peptides. It particularly inhibits the phosphorylation of 4E-BP1 and p27 Kip1 by Pim protein kinases. This compound is valuable in cancer research, with a notable application in studying prostate cancer [1]. Target: Pim. Smiles: COc1ccc(C=C2SC(=O)NC2=O)cc1. References: Charles D. Smith, et al. Inhibitors of PIM-1 Protein Kinases, Compositions and Methods for Treating Prostate Cancer. Patent US20110263664A1.
This website uses cookies, which are necessary for the technical operation of the website and are always set. Other cookies, which increase the usability of this website, serve for direct advertising or simplify interaction with other websites and social networks, will only be used with your consent.
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