Phenylethyl 3-methylcaffeate

Phenylethyl 3-methylcaffeate is a caffeic acid ester that has been found in propolis, a resin produced by honeybees, and has anticancer activity. Dietary administration of phenylethyl 3-methylcaffeate (750 ppm) reduces the incidence of both invasive and non-invasive colonic adenocarcinomas and the activity of colonic mucosal and tumor phosphatidylinositol-specific phospholipase C (PI-PLC) in a rat model of azoxymethane-induced carcinogenesis. It also increases intratumoral apoptosis in a rat model of azoxymethane-induced carcinogenesis.Formal Name: 3-(4-hydroxy-3-methoxyphenyl)-2-propenoic acid, 2-phenylethyl ester. CAS Number: 71835-85-3. Synonyms: NSC 666255, NSC 671193, Phenethyl Ferulate, 2-Phenylethyl Ferulate, beta-Phenethyl Ferulate. Molecular Formula: C18H18O4. Formula Weight: 298.3. Purity: >98%. Formulation: (Request formulation change), A solid. Solubility: Acetonitrile: Soluble, Methanol: Soluble. SMILES: O=C(C=CC1=CC=C(C(OC)=C1)O)OCCC2=CC=CC=C2. InChi Code: InChI=1S/C18H18O4/c1-21-17-13-15(7-9-16(17)19)8-10-18(20)22-12-11-14-5-3-2-4-6-14/h2-10,13,19H,11-12H2,1H3. InChi Key: CZQNYPBIOHVQQN-UHFFFAOYSA-N. Origin: Synthetic.