PF15 | CAS 2892631-70-6 | TargetMol

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Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
TGM-T74259-5mg	5 mg				7 - 10 business days*		-
TGM-T74259-50mg	50 mg				7 - 10 business days*		-

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Description: PF15, a selective FLT3-ITD degrader, serves as a PROTAC (proteolysis targeting... more

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Product information "PF15"

Description: PF15, a selective FLT3-ITD degrader, serves as a PROTAC (proteolysis targeting chimera) tethering ligands for FLT3 kinase and CRBN. It exhibits a degradation concentration 50 (DC50) of 76.7 nM and notably impedes the proliferation of FLT3-ITD-positive cells. PF15 also reduces phosphorylation levels of FLT3 and STAT5 and demonstrates efficacy in inhibiting tumor growth in mouse models, suggesting potential applications in leukemia research [1]. Target: PROTACs

Supplier:	TargetMol
Supplier-Nr:	T74259

Properties

MW:	855.94 D
Formula:	C44H49N13O6

Database Information

CAS :

2892631-70-6| Matching products

Handling & Safety

Storage:	-20°C
Shipping:	+20°C (International: +4°C)

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Our products are for laboratory research use only: Not for administration to humans!

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