Pemetrexed disodium hemipenta hydrate
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You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Description: Pemetrexed disodium hemipenta hydrate (LY-231514 Disodium Hydrate) is a new-type... more
Product information "Pemetrexed disodium hemipenta hydrate"
Description: Pemetrexed disodium hemipenta hydrate (LY-231514 Disodium Hydrate) is a new-type antifolate and antimetabolite for TS, DHFR, and GARFT. The Ki of Pemetrexed Disodium Hydrate for TS, DHFR and GARFT is 1.3 nM, 7.2 nM and 65 nM, respectively. Target: Apoptosis, DNA/RNA Synthesis, Autophagy, DHFR, Antifolate. Smiles: O.O.O.O.O.[Na+].[Na+].[Na+].[Na+].Nc1nc(=O)c2c(CCc3ccc(cc3)C(=O)N[C@@H](CCC([O-])=O)C([O-])=O)c[nH]c2[nH]1.Nc1nc(=O)c2c(CCc3ccc(cc3)C(=O)N[C@@H](CCC([O-])=O)C([O-])=O)c[nH]c2[nH]1. References: Shih C, et al. Cancer Res. 1997, 57(6), 1116-1123.
| Keywords: | Pemetrexed sodium hydrate, LY-231514 Disodium Hydrate, Pemetrexed Disodium Hydrate |
| Supplier: | TargetMol |
| Supplier-Nr: | T6226 |
Properties
| Application: | Targets thymidylate synthase [EC:2.1.1.45] (thyA, TYMS) |
| MW: | 518.43 D |
| Formula: | C20H21N5O6·2Na·5/2H2O |
Database Information
| CAS : | 357166-30-4| Matching products |
| KEGG ID : | K00287 | Matching products |
| Protein Atlas Nr. : | Nucleotides & Co |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +4°C (International: +4°C) |
| Signal Word: | Danger |
| GHS Hazard Pictograms: |
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| H Phrases: | H341, H360 |
| P Phrases: | P201, P202, P280, P308+313, P405, P501 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
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