Palmarumycin C3

Palmarumycin C3 is a spirobisnaphthalene fungal metabolite that has been found in C. palmarum and has diverse biological activities. It is active against the bacteria A. tumefaciens, B. subtilis, P. lachrymans, R. solanacearum, S. haemolyticus, and X. vesicatoria (MICs = 6.25, 6.25, 12.5, 12.5, 6.25, and 6.25 µg/ml, respectively). Palmarumycin C3 is also active against the fungi M. microspora and E. repens, as well as the plant pathogenic fungi F. oxysporum and U. violacea, in agar diffusion assays when used at a concentration of 0.5 mg/disc. It scavenges DPPH (Cay-14805) radicals in cell-free assays and has antioxidant activity in a beta-carotene-linoleic acid bleaching assay (IC50s = 37.57 and 7.41 µg/ml, respectively).Formal Name: 1aR,7aS-dihydro-3,6-dihydroxy-spiro[naphth[2,3-b]oxirene-2(7H),2'-naphtho[1,8-de][1,3]dioxin]-7-one. CAS Number: 159934-11-9. Molecular Formula: C20H12O6. Formula Weight: 348.3. Purity: >95%. Formulation: (Request formulation change), A solid. SMILES: OC1=C2C3(OC4=CC=CC5=C4C(O3)=CC=C5)[C@@]6([H])[C@](C(C2=C(C=C1)O)=O)([H])O6. InChi Code: InChI=1S/C20H12O6/c21-10-7-8-11(22)16-15(10)17(23)18-19(24-18)20(16)25-12-5-1-3-9-4-2-6-13(26-20)14(9)12/h1-8,18-19,21-22H/t18-,19-/m1/s1. InChi Key: BDXBHYOFNNANPN-RTBURBONSA-N. Origin: Fungus/Sphaeropsidales sp..