Palbociclib
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You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Description: Palbociclib (PD 0332991) is a CDK inhibitor that inhibits CDK4 and CDK6 (IC50=11/16... more
Product information "Palbociclib"
Description: Palbociclib (PD 0332991) is a CDK inhibitor that inhibits CDK4 and CDK6 (IC50=11/16 nM) and is orally active. Palbociclib has anti-tumorigenic activity and has investigational potential for use in ER-positive and HER2-negative breast cancer. Target: CDK. Smiles: O=C1N(C=2C(C(C)=C1C(C)=O)=CN=C(NC3=CC=C(C=N3)N4CCNCC4)N2)C5CCCC5. References: Katsumi Y, et al. Sensitivity of malignant rhabdoid tumor cell lines to PD 0332991 is inversely correlated with p16 expression. Biochem Biophys Res Commun. 2011 Sep 16,413(1):62-8.
| Keywords: | PD 0332991 |
| Supplier: | TargetMol |
| Supplier-Nr: | T1785 |
Properties
| Application: | Antineoplastic, Cyclin-dependent kinase (CDK) inhibitor |
| MW: | 447.53 D |
| Formula: | C24H29N7O2 |
Database Information
| CAS : | 571190-30-2| Matching products |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +4°C (International: +4°C) |
| Signal Word: | Danger |
| GHS Hazard Pictograms: |
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| H Phrases: | H341, H360, H373 |
| P Phrases: | P201, P202, P260, P280, P314, P308+P313, P405, P501 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
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