PACMA 31
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You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Description: PACMA 31 is an irreversible and covalent inhibitor of protein disulfide isomerase... more
Product information "PACMA 31"
Description: PACMA 31 is an irreversible and covalent inhibitor of protein disulfide isomerase (PDI) with an IC50 of 10 µM. PACMA 31 significantly suppresses ovarian tumor growth and exhibits tumor targeting ability. Target: Others. Smiles: CCOC(=O)CNC(=O)C(N(C(=O)C#C)c1ccc(OC)cc1OC)c1cccs1. References: Xu S, et al. Discovery of an orally active small-molecule irreversible inhibitor of protein disulfide isomerase for ovarian cancer treatment. Proc Natl Acad Sci U S A. 2012,109(40):16348-16353.
| Supplier: | TargetMol |
| Supplier-Nr: | T41277 |
Properties
| Application: | PDI inhibitor |
| MW: | 430.47 D |
| Formula: | C21H22N2O6S |
Database Information
| CAS : | 1401089-31-3| Matching products |
| KEGG ID : | K09580 | Matching products |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +4°C (International: +4°C) |
| Signal Word: | Danger |
| GHS Hazard Pictograms: |
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| H Phrases: | H301 |
| P Phrases: | P264, P270, P301+310, P321, P330, P405, P501 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
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