P7C3
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You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Description: The P7C3 class of neuroprotective aminopropyl carbazoles has been shown to block... more
Product information "P7C3"
Description: The P7C3 class of neuroprotective aminopropyl carbazoles has been shown to block neuronal cell death in models of neurodegeneration. We now show that P7C3 molecules additionally preserve axonal integrity after injury, before neuronal cell death occurs, in a rodent model of blast-mediated traumatic brain injury (TBI). This protective quality may be linked to the ability of P7C3 molecules to activate nicotinamide phosphoribosyltransferase, the rate-limiting enzyme in nicotinamide adenine dinucleotide salvage. Target: Others. Smiles: OC(CNc1ccccc1)Cn1c2ccc(Br)cc2c2cc(Br)ccc12. References: Wang G, et al. Cell. 2014, 158(6), 1324-1334.
| Supplier: | TargetMol |
| Supplier-Nr: | T1880 |
Properties
| Application: | Neuroprotective |
| MW: | 474.19 D |
| Formula: | C21H18Br2N2O |
Database Information
| CAS : | 301353-96-8| Matching products |
| KEGG ID : | K03462 | Matching products |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +4°C (International: +4°C) |
| Signal Word: | Danger |
| GHS Hazard Pictograms: |
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| H Phrases: | H301, H318 |
| P Phrases: | P264, P270, P280, P301+310, P305+351+338, P310, P321, P330, P405, P501 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
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