Oxyresveratrol powered by LipodisqTM Sterile Solution

Oxyresveratrol Lipodisq Sterile Solution is a ready-to-use nano-formulated aqueous solution. Oxyresveratrol is a naturally occurring analog of resveratrol. Potent antioxidant and free-radical scavenger. Shown to have neuroprotective activity against cerebral ischemia and against traumatic injury. Apoptosis inhibitor in transient cerebral ischemia. Inhibits viral DNA replication and late viral protein synthesis. Has depigmenting effects by effectively inhibiting tyrosinase activity, which catalyzes the rate-limiting step in synthesizing melanin pigments. Has anti-inflammatory properties based on inhibition of iNOS expression through down-regulation of NF-kB binding activity and significant inhibition of COX-2 activity. Anti-hyperlipidemic agent. Oxyresveratrol Lipodisq is based on a nanoparticle (11-40nm) drug delivery system comprising a discoidal phospholipid bilayer membrane stabilized by a chaperone molecule annulus. Internal properties of the phospholipid membrane support the disposition and stabilization of drug molecule candidates and preserve the native conformation of membrane molecules. The resulting encapsulated actives are rendered water-soluble and specialized for intra-cellular penetration/delivery via endosomal uptake mechanisms. Lipodisq solutions show a good safety profile and are suitable for in vitro and in vivo investigations.