OICR41114

OICR41114
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Item number Size Datasheet Manual SDS Delivery time Quantity Price
TGM-T203318-10mg 10 mg -

7 - 10 business days*

-
TGM-T203318-50mg 50 mg -

7 - 10 business days*

-
 
Description: OICR41114 (PROTAC4) is a PROTAC degrader targeting WDR5. It effectively degrades... more
Product information "OICR41114"
Description: OICR41114 (PROTAC4) is a PROTAC degrader targeting WDR5. It effectively degrades endogenous WDR5 with an EC50 of 40 nM and a Dmax of 49%. The degradation of HiBiT-tagged WDR5 by OICR41114 occurs in a proteasome-dependent manner. This compound is composed of a target protein ligand, Dimethyl-F-OICR-9429-COOH, an E3 ligase ligand, OICR-8268-acrylic acid, and a PROTAC linker, Amino-PEG9-amine. Notably, the conjugate of the E3 ligase ligand and the linker is OICR-8268-acrylic acid-amino-PEG9-amine.
Supplier: TargetMol
Supplier-Nr: T203318

Properties

MW: 1475.36 D
Formula: C70H83Cl2F6N9O15

Database Information

Handling & Safety

Storage: +4°C
Shipping: +20°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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