Nicotianamine

Nicotianamine is a metal chelator and phytosiderophore precursor produced in plants that has a role in the uptake, translocation, and intracellular transport of metals. Treating lettuce (L. sativa) with a Cu(OH)2-based pesticide raises nicotianamine levels 12- to 27-fold compared to non-pesticide treated plants. Nicotianamine also inhibits rabbit angiotensin-coverting enzyme (ACE) (IC50 = 0.26 µM) and human recombinant ACE2 (IC50 = 84 nM).Formal Name: alphaS-[[(3S)-3-amino-3-carboxypropyl]amino]-2S-carboxy-1-azetidinebutanoic acid. CAS Number: 34441-14-0. Molecular Formula: C12H21N3O6. Formula Weight: 303.3. Purity: >95%. Formulation: (Request formulation change), A solid. Solubility: Methanol: slightly soluble, Water: slightly soluble. SMILES: OC([C@@H](NCC[C@H](N)C(O)=O)CCN1[C@H](C(O)=O)CC1)=O. InChi Code: InChI=1S/C12H21N3O6/c13-7(10(16)17)1-4-14-8(11(18)19)2-5-15-6-3-9(15)12(20)21/h7-9,14H,1-6,13H2,(H,16,17)(H,18,19)(H,20,21)/t7-,8-,9-/m0/s1. InChi Key: KRGPXXHMOXVMMM-CIUDSAMLSA-N.