Nicarbazine

Nicarbazine is a coccidiostat. It is composed of an equimolar complex of 4,4'-dinitrocarbanilide (DNC) and 2-hydroxy-4,6-dimethylpyrimidine (HDP). Nicarbazine (0.01-0.04% in the diet) prevents mortality of, and suppresses oocyst production in, chickens infected with the parasites E. acervulina, E. necatrix, E. tenella, and P. gallinaceum. Dietary administration of nicarbazine (100 ppm) decreases the production, weight, and pigmentation of eggs produced by broiler breeder chickens. Formulations containing nicarbazine have been used in the prevention of coccidiosis in chickens.Formal Name: N,N'-bis(4-nitrophenyl)-urea, compd. with 4,6-dimethyl-2(1H)-pyrimidinone. CAS Number: 330-95-0. Synonyms: MK 75, NCZ, NSC 7171, Nicarbazin. Molecular Formula: C13H10N4O5 . C6H8N2O. Formula Weight: 426.4. Purity: >95%. Formulation: (Request formulation change), A solid. Solubility: DMSO: slightly soluble. lambdamax: 222, 341 nm. SMILES: O=C1N=C(C)C=C(C)N1.O=C(NC2=CC=C([N+]([O-])=O)C=C2)NC3=CC=C([N+]([O-])=O)C=C3. InChi Code: InChI=1S/C13H10N4O5.C6H8N2O/c18-13(14-9-1-5-11(6-2-9)16(19)20)15-10-3-7-12(8-4-10)17(21)22,1-4-3-5(2)8-6(9)7-4/h1-8H,(H2,14,15,18),3H,1-2H3,(H,7,8,9). InChi Key: UKHWDRMMMYWSFL-UHFFFAOYSA-N.