NI-42

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Item number	Size	Delivery time	Price
TGM-T16321-5mg	5 mg	5 - 10 business days*	37.00€
TGM-T16321-1mL	1 ml	5 - 10 business days*	40.00€
TGM-T16321-10mg	10 mg	5 - 10 business days*	59.00€
TGM-T16321-25mg	25 mg	5 - 10 business days*	121.00€
TGM-T16321-50mg	50 mg	5 - 10 business days*	186.00€
TGM-T16321-100mg	100 mg	5 - 10 business days*	291.00€

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Description: NI-42 is a structurally orthogonal chemical probe for the BRPFs and is biased. It... more

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Product information "NI-42"

Description: NI-42 is a structurally orthogonal chemical probe for the BRPFs and is biased. It effective inhibitor of the BRD of the BRPFs (IC50s of BRPF1/2/3=7.9/48/260 nM, Kds of BRPF1/2/3=40/210/940 nM). It also has excellent selectivity over nonclass IV BRD proteins. Target: Epigenetic Reader Domain. Smiles: Cc1cc2cc(NS(=O)(=O)c3ccc(cc3)C#N)ccc2n(C)c1=O. References: Igoe N, et al. Design of a Biased Potent Small Molecule Inhibitor of the Bromodomain and PHD Finger-Containing (BRPF) Proteins Suitable for Cellular and in Vivo Studies. J Med Chem. 2017 Jan 26,60(2):668-680.

Supplier:	TargetMol
Supplier-Nr:	T16321

Properties

Application:	Peregrin/BRPF1 inhibitor
MW:	353.39 D
Formula:	C18H15N3O3S

Database Information

CAS :	1884640-99-6\| Matching products
KEGG ID :	K11348 \| Matching products

Handling & Safety

Storage:	-20°C
Shipping:	+20°C (International: +4°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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