NH125

NH125
Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay10011250-1 1 mg -

6 - 10 business days*

40.00€
Cay10011250-5 5 mg -

6 - 10 business days*

120.00€
Cay10011250-10 10 mg -

6 - 10 business days*

160.00€
Cay10011250-25 25 mg -

6 - 10 business days*

350.00€
 
NH125 is an imidazole that has potent antibacterial properties in drug-resistant bacteria. In... more
Product information "NH125"
NH125 is an imidazole that has potent antibacterial properties in drug-resistant bacteria. In bacteria, NH125 inhibits several histidine kinases, inhibiting YycG with an IC50 of 6.6 µM. NH125 also decreases the viability of several cancer cell lines with IC50 values ranging from 0.7-4.7 µM. In mammalian cells, NH125 strongly inhibits eEF-2K (IC50 = 60 nM), with weaker effects on protein kinase C (IC50 = 7.5 µM), protein kinase A (IC50 = 80 µM), and calmodulin-dependent kinase II (IC50 = 100 µM). Formal Name: 1-hexadecyl-2-methyl-3-(phenylmethyl)-1H-imidazolium-iodide. CAS Number: 278603-08-0. Molecular Formula: C27H45IN2. Formula Weight: 524.6. Purity: >95%. Formulation: A crystalline solid. Solubility: DMF: 15 mg/ml, DMF:PBS (pH 7.2) (1:2): 0.3 mg/ml, DMSO: 2.5 mg/ml, Ethanol: 5 mg/ml. lambdamax: 214 nm. SMILES: c1cccc(c1)Cn1cc[n+](c1C)CCCCCCCCCCCCCCCC.[I-]. InChi Code: InChI=1S/C27H45N2.HI/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-19-22-28-23-24-29(26(28)2)25-27-20-17-16-18-21-27,/h16-18,20-21,23-24H,3-15,19,22,25H2,1-2H3,1H/q+1,/p-1. InChi Key: RVWOHCBHAGBLLT-UHFFFAOYSA-M.
Keywords: 1-hexadecyl-2-methyl-3-(phenylmethyl)-1H-imidazolium-iodide
Supplier: Cayman Chemical
Supplier-Nr: 10011250

Properties

Application: EEF-2K inhibitor
MW: 524.6 D
Formula: C27H45IN2
Purity: >95%
Format: Crystalline Solid

Database Information

CAS : 278603-08-0| Find alternatives
KEGG ID : K08292 | Find alternatives

Handling & Safety

Storage: -20°C
Shipping: +20°C (International: -20°C)
Signal Word: Warning
GHS Hazard Pictograms:
H Phrases: H315, H319, H335
P Phrases: P261, P264, P271, P280, P302+352, P304+340, P305+351+338, P312, P321, P332+313, P337+313, P362+364, P403+233, P405, P501
Caution
Our products are for laboratory research use only: Not for administration to humans!
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