NBD-Fructose

NBD-Fructose is a fluorescent derivative of fructose that is formed by coupling NBD-chloride with the amine group of amino fructose. It has been used to monitor fructose uptake by the GLUT5 transporter in MCF-7, MDA-MB-435, and MDA-MB-231 human breast cancer cells. NBD-Fructose displays excitation/emission maxima of 472/538 nm, respectively.Formal Name: 1-deoxy-1-[(7-nitro-2,1,3-benzoxadiazol-4-yl)amino]-D-fructose. CAS Number: 940961-04-6. Synonyms: 1-NBDF, 1-(7-nitro-1,2,3-benzadiazole)-Fructose. Molecular Formula: C12H14N4O8. Formula Weight: 342.3. Purity: >95% (sum of isomers). Emission: 538 nm. Excitation: 472 nm. Formulation: (Request formulation change), A crystalline solid. Solubility: PBS (pH 7.2): 30 mg/ml, Water: 30 mg/ml. lambdamax: 226, 330, 461 nm. SMILES: O=C([C@@H](O)[C@H](O)[C@H](O)CO)CNC1=CC=C([N+]([O-])=O)C2=NON=C21. InChi Code: InChI=1S/C12H14N4O8/c17-4-8(19)12(21)11(20)7(18)3-13-5-1-2-6(16(22)23)10-9(5)14-24-15-10/h1-2,8,11-13,17,19-21H,3-4H2/t8-,11-,12-/m1/s1. InChi Key: PYUWRKIMILVYHE-GGZOMVNGSA-N.