Nalpha-Benzoyl-DL-Arginine-pNA (hydrochloride)

Nalpha-Benzoyl-DL-arginine-pNA (DL-BAPNA) is a colorimetric substrate for serine proteases, including beta-secretase 1 (BACE1), calpain, and papain. Serine proteases bind to and cleave DL-BAPNA to release p-nitroanilide (pNA), which can be quantified by colorimetric detection at 405 nm as a measure of serine protease activity.Formal Name: N-[4-[(aminoiminomethyl)amino]-1-[[(4-nitrophenyl)amino]carbonyl]butyl]-benzamide, monohydrochloride. CAS Number: 911-77-3. Synonyms: Nalpha-Benzoyl-DL-Arginine-p-nitroanilide, DL-BAPNA, NSC 83264. Molecular Formula: C19H22N6O4 . HCl. Formula Weight: 434.9. Purity: >98%. Formulation: (Request formulation change), A solid. Solubility: DMF: 1 mg/ml, DMSO: 10 mg/ml, DMSO:PBS (pH 7.2) (1:8): 0.11 mg/ml. lambdamax: 225, 312 nm. SMILES: O=C(C1=CC=CC=C1)NC(CCCNC(N)=N)C(NC2=CC=C([N+]([O-])=O)C=C2)=O.Cl. InChi Code: InChI=1S/C19H22N6O4.ClH/c20-19(21)22-12-4-7-16(24-17(26)13-5-2-1-3-6-13)18(27)23-14-8-10-15(11-9-14)25(28)29,/h1-3,5-6,8-11,16H,4,7,12H2,(H,23,27)(H,24,26)(H4,20,21,22),1H. InChi Key: DEOKFPFLXFNAON-UHFFFAOYSA-N.