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Nahlsgen is an inhibitor of gamma-glutamyl transpeptidase (GGT, Ki = 170 µM). It increases left ventricular developed pressure (LVDP), decreases left ventricular end-diastolic pressure (LVEDP), and reduces left ventricle homogenate malondialdehyde (MDA), coronary perfusate norepinephrine, and cardiac oxygen radical levels in perfused isolated rat hearts in a model of ischemia-reperfusion injury when used at a concentration of 1 µM. Nahlsgen (5 mg/kg) inhibits IL-13-induced airway constriction in a mouse model of allergic asthma. Formulations containing nahlsgen have been used in cosmetics and creams.. Solulibility: DMSO: Sparingly soluble: 1-10 mg/ml: PBS pH 7.2: Sparingly soluble: 1-10 mg/ml.
This website uses cookies, which are necessary for the technical operation of the website and are always set. Other cookies, which increase the usability of this website, serve for direct advertising or simplify interaction with other websites and social networks, will only be used with your consent.
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