N6-Methyladenosine

N6-Methyladenosine is an adenosine analog. It inhibits epinephrine-induced contraction of isolated guinea pig ileum and thoracic aorta when used at a concentration of 10 µM. N6-Methyladenosine (1 mg/kg, i.v.) decreases arterial blood pressure and renal blood flow and increases peripheral resistance in anesthetized dogs. It also inhibits tumor growth in the C3H/ST and C3HB/ST mouse models of spontaneous mammary adenocarcinomas. N6-Methyladenosine is also the most prevelant mRNA modification in eukaryotes and has roles in cell viability and development.Formal Name: N-methyl-adenosine. CAS Number: 1867-73-8. Synonyms: NSC 29409. Molecular Formula: C11H15N5O4. Formula Weight: 281.3. Purity: >95%. Formulation: (Request formulation change), A crystalline solid. lambdamax: 266 nm. SMILES: [H][C@]1(O[C@H](CO)[C@@H](O)[C@H]1O)N2C=NC3=C(NC)N=CN=C32. InChi Code: InChI=1S/C11H15N5O4/c1-12-9-6-10(14-3-13-9)16(4-15-6)11-8(19)7(18)5(2-17)20-11/h3-5,7-8,11,17-19H,2H2,1H3,(H,12,13,14)/t5-,7-,8-,11-/m1/s1. InChi Key: VQAYFKKCNSOZKM-IOSLPCCCSA-N.