N-Nonanoyl-DL-homoserine lactone

Source/Host Chemicals: Synthetic. Appearance: White to off-white solid. Solubility: Soluble in DMSO or DMF (20mg/ml). Identity: Determined by 1H-NMR. InChi Key: OMPXHNXRUVEQDO-UHFFFAOYSA-N Smiles: O=C1C(NC(CCCCCCCC)=O)CCO1 N-Nonanoyl-DL-homoserine lactone is a small diffusible signaling molecule involved in quorum sensing, controlling gene expression and affecting cellular metabolism. The diverse applications of this kind of molecule include regulation of virulence in general, infection prevention, and formation of biofilms. Product References: [1] A.L. Schaefer, eet al., J. Bacteriol. 178, 2897 (1996) , [2] L. Passador, et al., J. Bacteriol. 178, 5995 (1996) , [3] J.J. Michels, et al., J. Chromatogr. A 898, 153 (2000) , [4] G. Brader, et al., J. Biol. Chem. 280, 10403 (2005) , [5] K.-G. Chan, et al., BMC Microbiol. 11, 51 (2011) , [6] T.P.T. Hoang, et al., Anal. Bioanal. Chem. 412, 2261 (2020) , [7] J. Xue, et al., Biofilm Microbiomes 7, 53 (2021)